Artificial Molecular Machine Manufactures Proteins

The construction of peptides (components of protein) with amino acids is done biologically by ribosomes. An army of 10^18 artificial molecular machines constructed milligrams of a specific peptide simultaneously from amino acids in their path. These machines were designed based on rotaxane which is similar to a ring on an axle. They constructed the peptides from amino acids it picked up from a strand they followed. This is a large step toward nano-scale machines that can create copies of themselves and do more complex stuff.

Original Publication: Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine

English: Illustration of tRNA building peptide...

English: Illustration of tRNA building peptide chain (Photo credit: Wikipedia)

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